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Paper News and Science Links...

SFN's "The History of Neuroscience in Autobiography"

URMC Press Release regarding the 5-FU paper (Read more).

The latest news surrounding a recently published 5-FU paper by Mark, Margot, Roulan Han and colleagues (Read more).

Selected Publications

Han R, Yang YM, Dietrich J, Luebke A, Mayer-Pröschel M, Noble M.
Systemic 5-fluorouracil treatment causes a syndrome of delayed myelin destruction in the central nervous system. J Biol. 2008 Apr 22;7(4):12 [Epub ahead of print]

Li Z, Dong T, Pröschel C, Noble M. Chemically diverse toxicants converge on Fyn and c-Cbl to disrupt precursor cell function. PLoS Biol. 2007 Feb;5(2):e35. [abstract]


Noble M. Ethics in the trenches: a multifaceted analysis of the stem cell debate. Stem Cell Rev. 2005 Dec;1(4):345-76. [abstract]


Dietrich J, Han R, Yang Y, Mayer-Pröschel M, Noble M. CNS progenitor cells and oligodendrocytes are targets of chemotherapeutic agents in vitro and in vivo. J Biol. 2006;5(7):22. [abstract]


Jordan CT, Guzman ML, Noble M. Cancer stem cells. N Engl J Med. 2006 Sep 21;355(12):1253-61. Review. [abstract]


Hyrien O, Ambeskovic I, Mayer-Proschel M, Noble M, Yakovlev A. Stochastic modeling of oligodendrocyte generation in cell culture: model validation with time-lapse data. Theor Biol Med Model. 2006 May 17;3:21. [abstract]


Davies JE, Huang C, Proschel C, Noble M, Mayer-Proschel M, Davies SJ. Astrocytes derived from glial-restricted precursors promote spinal cord repair. J Biol. 2006;5(3):7. Epub 2006 Apr 27. [abstract]


Noble M. Implications for CNS repair of redox modulation of cell survival, division and differentiation. Curr Alzheimer Res. 2006 Feb;3(1):37-47. Review. [abstract]


Noble M, Mayer-Pröschel M, Pröschel C. Redox regulation of precursor cell function: insights and paradoxes. Antioxid Redox Signal. 2005 Nov-Dec;7(11-12):1456-67. Review. [abstract]


Hyrien O, Mayer-Pröschel M, Noble M, Yakovlev A. Estimating the life-span of oligodendrocytes from clonal data on their development in cell culture. Math Biosci. 2005 Feb;193(2):255-74. Epub 2005 Jan 22. [abstract]


Hyrien O, Mayer-Pröschel M, Noble M, Yakovlev A. A stochastic model to analyze clonal data on multi-type cell populations. Biometrics. 2005 Mar;61(1):199-207. [abstract]


Dietrich J, Lacagnina M, Gass D, Richfield E, Mayer-Pröschel M, Noble M, Torres C, Pröschel C. EIF2B5 mutations compromise GFAP+ astrocyte generation in vanishing white matter leukodystrophy. Nat Med. 2005 Mar;11(3):277-83. Epub 2005 Feb 20. [abstract]